Glossary

Biochemistry, molecular genetics, and biology glossary terms for Companion Sites.

capping

Capping occurs shortly after initiation of transcription, and is a stage of RNA processing in which the 5’ end of the nascent pre-mRNA is capped with a 7-methyl guanosine nucleotide, 7-methylguanylate.

The 5' cap is retained in mature mRNAs. Capping is required to protect the RNA transcript from degradation. It plays an important role in mRNA transport to the cytoplasm and in the initiation of protein synthesis (translation).

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