Glossary

Biochemistry, molecular genetics, and biology glossary terms for Companion Sites.

cellular stress response

The cellular stress response (heat-shock response) protects organisms from damage resulting from environmental stressors such as heat, UV light, trace metals, and xenobiotics.

Physical or chemical stress inactivates or down-regulates many genes, including many housekeeping genes, while up-regulating stress genes that perform orchestrated induction of key proteins necessary for cellular protein repair and degradation systems. Stress genes are highly conserved in biological evolution and play similar roles in organisms from bacteria to humans.

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