wortmannin
Wortmannin is a fungal metabolite that is a specific inhibitor of PI3Ks, though it can also inhibit mTOR, DNA-PK, some phosphatidylinositol 4-kinases, myosin light chain kinase (MLCK) and mitogen-activated protein kinase (MAPK).
Because Akt is located downstream of PI3K, Akt functions as part of a wortmannin-sensitive signaling pathway.
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Because Akt is located downstream of PI3K, Akt functions as part of a wortmannin-sensitive signaling pathway.
Glossary : A . B . C . D . E . F . G . H . I . J . K . L . M . N . O . P . Q . R . S . T . U . V . W . X . Y . Z .Gray Sites • Abiogenesis & Evolution • Algorithms of Evolution • Cell Biology • Chemistry of Life • Cyanobacteria • Enzymes • Evo Devo • Immunology • Mechanisms of Evolution • Molecular Biology • Origin of Life • Paleogeology • Refuting ID • Serial Endosymbiosis • Stromatolites • Taxonomy Phylogeny • Virus • White Sites • Diagrams & Tables • Eubacteria & Archaea • Molecule • Molecular Paths • Pathways • Photosynthesis • Black Sites • Endosymbiosis • Organics •