proto-oncogene

Proto-oncogenes participate in a variety of normal cellular functions, but have the potential to tranform into cellular oncogenes when damaged.

Proto-oncogenes normally function in the various signal transduction cascades that regulate cell growth, proliferation and differentiation. Cellular proto-oncogenes resident in transforming retroviruses are designated as c- (cellular origin) as opposed to v- (retroviral origin). Oncogenes are malignantly transformed proto-oncogenes. Table  Oncogenes Proto-oncogenes.

¤ c-Fos ¤ c-Jun ¤ c-Myc ¤ c-Sis ¤ c-Src ¤ Ras ¤ Rb ¤ Src ¤ v-Src ¤

Glossary items :
□-□ A □-□ B □-□ C □-□ D □-□ E □-□ F □-□ G □-□ H □-□ I □-□ J □-□ K □-□ L □-□ M □-□ N □-□ O □-□ P □-□ Q □-□ R □-□ S □-□ T □-□ U □-□ V □-□ W □-□ X □-□ Y □-□ Z □-□

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