splice-sites
Splice-sites are the intron-exon junctions in the precursor mRNA of eukaryotes, and are recognized by trans-acting factors (prokaryotic RNAs are mostly polycistronic).
In constitutive nuclear pre-mRNA splicing the intronic sequences are excised and the exons are ligated to generate the mature, spliced mRNA.
Pre-mRNA splicing is a form of RNA processing, which yields a mature mRNA comprising the coding exons that direct sequencing of amino acids inserted into elongating polypeptides during cytoplasmic translation at ribosomes. However, a cell typically splices a single mRNA transcript in multiple ways to generate an assortment of proteins. Alternatively spliced introns tend to lie between those exonal segments of a gene that encode the functional units, or domains, of a protein (ORF).
The length and sequence of nucleotides in nuclear pre-mRNA introns is highly variable, except for the short conserved sequences at the 5´ and 3´ splice sites and the branch points. These splice sites immediately surrounding the intron-exon junction can be regarded as consensus sequences.
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In constitutive nuclear pre-mRNA splicing the intronic sequences are excised and the exons are ligated to generate the mature, spliced mRNA.
Pre-mRNA splicing is a form of RNA processing, which yields a mature mRNA comprising the coding exons that direct sequencing of amino acids inserted into elongating polypeptides during cytoplasmic translation at ribosomes. However, a cell typically splices a single mRNA transcript in multiple ways to generate an assortment of proteins. Alternatively spliced introns tend to lie between those exonal segments of a gene that encode the functional units, or domains, of a protein (ORF).
The length and sequence of nucleotides in nuclear pre-mRNA introns is highly variable, except for the short conserved sequences at the 5´ and 3´ splice sites and the branch points. These splice sites immediately surrounding the intron-exon junction can be regarded as consensus sequences.
Alphabetic links to Glossary items:
◦ A ◦ B ◦ C ◦ D ◦ E ◦ F ◦ G ◦ H ◦ I ◦ J ◦ K ◦ L ◦ M ◦ N ◦ O ◦ P ◦ Q ◦ R ◦ S ◦ T ◦ U ◦ V ◦ W ◦ X ◦ Y ◦ Z ◦
Gray Sites • Abiogenesis & Evolution • Algorithms of Evolution • Cell Biology • Chemistry of Life • Cyanobacteria • Enzymes • Evo Devo • Immunology • Mechanisms of Evolution • Molecular Biology • Origin of Life • Paleogeology • Refuting ID • Serial Endosymbiosis • Stromatolites • Taxonomy Phylogeny • Virus • White Sites • Diagrams & Tables • Eubacteria & Archaea • Molecule • Molecular Paths • Pathways • Photosynthesis • Black Sites • Endosymbiosis • Organics •