Glossary

Biochemistry, molecular genetics, and biology glossary terms for Companion Sites.

transcription factors

Transcription factors are proteins that bind to DNA at specific promoter or enhancer or response element sequences or sites, at which they regulate transcription. As such they are required for the recognition of specific stimulatory sequences in eukaryotic genes by RNA polymerases. Transcription factors can be selectively activated or deactivated by other proteins, often as the final step in signal transduction.

Three types of transcription factor are recognized:general transcription factors, upstream transcription factors, and inducible transcription factors.

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